Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478279 | 0.60 | MAP4K4 (0.36) | DRD2POLBALDH1A1 | |
| SCHEMBL6987370 | 0.59 | — | — | |
| SCHEMBL17525458 | 0.59 | HRH3 (0.59) | HRH3POLBALDH1A1CYP1A2 | |
| SCHEMBL4607124 | 0.59 | HRH3 (0.47) | HRH3ALDH1A1CYP2D6 | |
| SCHEMBL10531233 | 0.58 | — | — | |
| SCHEMBL13722590 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL11639840 | 0.58 | HSD17B10 (0.73) | HRH3DRD2HSD17B10MEN1KMT2A | |
| SCHEMBL2394310 | 0.57 | — | — | |
| SCHEMBL238611 | 0.57 | HRH3 (0.62) | HRH3POLBALDH1A1CYP1A2 | |
| SCHEMBL2616296 | 0.56 | PRMT6 (0.48) | HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |