Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | FNTB | P49356 | 3/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303334 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL1147839 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL5087526 | 0.98 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL7765496 | 0.98 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL462401 | 0.98 | NOD1 (0.48) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL25411986 | 0.98 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL9341319 | 0.98 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL9341321 | 0.98 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL5087530 | 0.98 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BLMNA | |
| SCHEMBL462399 | 0.98 | NOD1 (0.48) | NOD1FNTAFNTBPGGT1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178624-B | Isocyanate stabilizer, isocyanate composition and polyurethane resin | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-116178624-A | Isocyanate stabilizer, isocyanate composition and polyurethane resin | 万华化学集团股份有限公司 | 2023-05-30 | — | — | CN | claimed |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | claimed |
| EP-3618819-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-11 | — | — | EP | claimed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | claimed |
| CN-110831584-A | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2020-02-21 | — | — | CN | claimed |
| EP-2326724-B1 | PRODUCING METHIONINE WITHOUT N-ACYL-METHIONINE | EVONIK DEGUSSA GMBH (DE) | 2019-05-22 | — | — | EP | claimed |
| WO-2018204713-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | EXCIVA UG (HAFTUNGSBESCHRÄNKT) (DE) | 2018-11-08 | — | — | WO | claimed |
| CN-106456633-A | Sugar metabolism improving agent | 三得利控股株式会社 | 2017-02-22 | — | — | CN | claimed |
| CN-106034441-A | Method for performing raw soil greening on sulfate-contained sandy soil through soil improvement fertilizer comprising biological agent | 山东胜伟园林科技有限公司 | 2016-10-26 | — | — | CN | claimed |
| WO-2010020681-A1 | PRODUCING METHIONINE WITHOUT N-ACYL-METHIONINE | METABOLIC EXPLORER (FR) | 2010-02-25 | — | — | WO | claimed |
| CN-101347877-A | Paste-shaped welding combination | XIAMEN JISHIYU FUSE SOLDER CO (CN) | 2009-01-21 | — | — | CN | claimed |
| US-7368600-B2 | Method for production of methionine from homoserine | DEGUSSA GMBH (DE) | 2008-05-06 | — | — | US | claimed |
| US-20070190622-A1 | Method for production of methionine from homoserine | DEGUSSA GMBH (DE) | 2007-08-16 | — | — | US | claimed |
| US-6664083-B2 | Adjusting stereospecificiy of amino acid seqences; obtain sample polypeptides, incubate with enzyme, recover stereospecific compound | DAICHEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-16 | — | — | US | claimed |
| US-6437175-B2 | MILD REACTION CONDITIONS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2002-08-20 | — | — | US | claimed |
| US-20020102662-A1 | Methods for racemizing N-acylamino acids and producing optically active amino acids | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-01 | — | — | US | claimed |
| EP-1130108-A1 | Methods for racemizing N-acylamino acids and producing optically active amino acids | Daicel Chemical Industries, Ltd. (JP) | 2001-09-05 | — | — | EP | claimed |
| US-4241085-A | N-ACYL-METHIONINE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-12-23 | — | — | US | claimed |
| US-4093740-A | N-ACYL-METHIONINE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSIER (DT) | 1978-06-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | NOD1 2222/4885FNTA 2052/4885FNTB 2252/4885 |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2C, HTR2A, HTR3A | NOD1 1553/4885FNTA 3473/4885FNTB 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.