Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123199 | 0.96 | ERAP2 (0.63) | ERAP2MAGI3ECE1MMP1MMP2 | |
| SCHEMBL31171681 | 0.94 | CASP1 (0.57) | ERAP2CASP1CASP3CASP7ERBB2 | |
| SCHEMBL31171635 | 0.92 | CASP1 (0.55) | ERAP2CASP1CASP3CASP7ERBB2 | |
| SCHEMBL31171653 | 0.91 | CASP1 (0.58) | ERAP2CASP1CASP3CASP7ERBB2 | |
| SCHEMBL29828545 | 0.90 | KDM4E (0.57) | ERAP2CASP1CASP3CASP7EDNRA | |
| SCHEMBL29531522 | 0.88 | ERAP2 (0.60) | ERAP2ERBB2MAGI3ECE1ACE | |
| SCHEMBL31720961 | 0.88 | ERAP2 (0.60) | ERAP2ERBB2MAGI3ECE1ACE | |
| SCHEMBL29394599 | 0.88 | ERAP2 (0.60) | ERAP2CASP1CASP3CASP7MAGI3 | |
| SCHEMBL29559633 | 0.87 | ACE (0.62) | ERAP2MAGI3ECE1MMP9MMP8 | |
| SCHEMBL31220181 | 0.87 | CASP1 (0.60) | ERAP2CASP1CASP3CASP7EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852338-A | Oral micromolecular salvianic acid derivatives, and preparation method and application thereof | 首都医科大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-115887654-A | Magnetic microbubble for removing microthrombus and interventional microthrombus removing device | 清华大学 | 2023-04-04 | — | — | CN | disclosed |