Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549765 | 0.84 | KMT2A (0.46) | BCAT2HCRTR1HCRTR2TSHRKMT2A | |
| SCHEMBL7796946 | 0.84 | BACE1 (0.43) | BCAT2ALDH1A1HCRTR1HCRTR2TSHR | |
| SCHEMBL6637451 | 0.83 | ESR1 (0.41) | ALDH1A1CYP3A4MAPTCYP2C19BLM | |
| SCHEMBL6633897 | 0.83 | MAPK14 (0.45) | ALDH1A1POLBCYP3A4MAPTCYP2C19 | |
| SCHEMBL6634313 | 0.81 | GRM2 (0.41) | ALDH1A1TSHRMAPTCYP2C19HSD17B10 | |
| SCHEMBL10434450 | 0.81 | LMNA (0.45) | ALDH1A1TSHRPOLBHSD17B10LMNA | |
| SCHEMBL6632966 | 0.81 | IKBKB (0.41) | ALDH1A1CYP2C19HSD17B10FGFR1SRC | |
| SCHEMBL3975038 | 0.81 | MAPK14 (0.47) | IKBKBCHUKIKBKEPKMYT1 | |
| SCHEMBL28480938 | 0.81 | MKNK1 (0.53) | ALDH1A1CYP3A4CYP2C19LMNAIKBKB | |
| SCHEMBL7279084 | 0.81 | SMN1; SMN2 (0.44) | BCAT2ALDH1A1HCRTR1HCRTR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535371-B | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2025-02-18 | — | — | CN | claimed |
| CN-116535371-A | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | claimed |
| EP-4596548-A1 | NURR1 MODULATORS | Ludwig-Maximilians-Universität (DE) | 2025-08-06 | — | — | EP | disclosed |
| CN-116535371-B | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-116535371-A | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| US-9562019-B2 | Substituted pyridazines as EGFR and/or KRAS inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-02-07 | — | — | US | disclosed |
| EP-2518063-B1 | Pyridazinones and furan-containing compounds | SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2099770-B1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | SLOAN KETTERING INST CANCER (US) | 2015-06-10 | — | — | EP | disclosed |
| US-20130131062-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | DJABALLAH HAKIM (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2518063-A1 | Pyridazinones and furan-containing compounds | Sloan-Kettering Institute For Cancer Research (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20100210649-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-08-19 | — | — | US | disclosed |
| EP-2099770-A2 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | Sloan-Kettering Institute for Cancer Research (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008080056-A2 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-1747214-A2 | DIHYDROBENZOTHIOPHENES | MERCK PATENT GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005108355-A2 | DIHYDROBENZOTHIOPHENES | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131062-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | DPYD, PDXK, TYMP | BCAT2 3142/4885ALDH1A1 761/4885ADORA2A 1379/4885 |
| US-20100210649-A1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | DPYD, PDXK, TYMP | BCAT2 3142/4885ALDH1A1 761/4885ADORA2A 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.