⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255652 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL4025170 | 0.73 | — | — | |
| SCHEMBL30389154 | 0.73 | — | — | |
| SCHEMBL1275114 | 0.66 | LOXL2 (0.38) | — | |
| SCHEMBL8579517 | 0.60 | LMNA (0.52) | — | |
| SCHEMBL8135 | 0.60 | — | — | |
| SCHEMBL29477151 | 0.60 | — | — | |
| SCHEMBL1198640 | 0.60 | — | — | |
| SCHEMBL31213588 | 0.60 | — | — | |
| SCHEMBL30304969 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147993-A1 | THIOPHENE COMPOUNDS WITH CYCLIC AMIDES, AND USES THEREOF | CAPULUS THERAPEUTICS, LLC | 2023-05-11 | — | — | US | disclosed |