Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204449 | 1.00 | HTT (0.53) | HTTSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10357783 | 0.86 | PTGS1 (0.45) | HTTSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10175303 | 0.84 | HTT (0.59) | HTTSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10684266 | 0.83 | HMGB1 (0.43) | LMNAMAPTESR1ALDH1A1KDM4E | |
| SCHEMBL28413744 | 0.82 | ALDH1A1 (0.48) | HPGDLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL29670017 | 0.82 | ALDH1A1 (0.48) | HPGDLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL9544691 | 0.81 | HTT (0.56) | HTTSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL11016647 | 0.78 | HTT (0.56) | HTTSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL9012657 | 0.77 | HTT (0.71) | HTTSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL6842046 | 0.77 | BCL2 (0.54) | HTTSMN1; SMN2HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892486-B | Hydroxyl-substituted benzophenone compound and preparation method and application thereof | 莆田学院 | 2023-04-18 | — | — | CN | claimed |
| CN-111892486-B | Hydroxyl-substituted benzophenone compound and preparation method and application thereof | 莆田学院 | 2023-04-18 | — | — | CN | disclosed |
| CN-111892486-B | Hydroxyl-substituted benzophenone compound and preparation method and application thereof | 莆田学院 | 2023-04-18 | — | — | CN | disclosed |