Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017133 | 1.00 | GLS (0.55) | GLSKCNH2 | |
| SCHEMBL29017131 | 1.00 | GLS (0.55) | GLSKCNH2 | |
| SCHEMBL29017144 | 0.93 | GLS (0.59) | GLSKCNH2 | |
| SCHEMBL29017110 | 0.91 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL29017108 | 0.91 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL29017163 | 0.88 | GLS (0.62) | GLSKCNH2 | |
| SCHEMBL29017195 | 0.86 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL29017188 | 0.84 | GLS (0.59) | GLSKCNH2 | |
| SCHEMBL29017191 | 0.84 | GLS (0.59) | GLSKCNH2 | |
| SCHEMBL29017220 | 0.84 | GLS (0.52) | GLSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594683-A | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |