Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.58 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.54 |
| ▸ | GRM5 | P41594 | 3/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417726 | 1.00 | PARP11 (0.58) | PARP11PARP10SRD5A1SRD5A2GRM5 | |
| SCHEMBL29631237 | 0.87 | PARP10 (0.58) | PARP11PARP10SRD5A1SRD5A2PDPK1 | |
| SCHEMBL20894239 | 0.87 | PARP10 (0.58) | PARP11PARP10SRD5A1SRD5A2PDPK1 | |
| SCHEMBL8885387 | 0.85 | PARP11 (0.49) | PARP11PARP10SRD5A1SRD5A2GRM5 | |
| SCHEMBL30421037 | 0.85 | PARP10 (0.57) | PARP11PARP10GRM5PRKACAPRKACG | |
| SCHEMBL1727165 | 0.85 | PARP11 (0.72) | PARP11PARP10GRM5PRKACAPRKACG | |
| SCHEMBL14332678 | 0.83 | SMYD3 (0.58) | SRD5A1SRD5A2GRM5KDM4EMAPT | |
| SCHEMBL12810163 | 0.83 | PARP10 (0.54) | PARP11PARP10GRM5PRKACAPRKACG | |
| SCHEMBL12683051 | 0.81 | PRKACA (0.58) | PARP11PARP10GRM5PRKACAPRKACG | |
| SCHEMBL30336933 | 0.81 | PRKACA (0.58) | PARP11PARP10GRM5PRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242073-A | PRMT5 inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |