Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.58 |
| ▸ | PARP1 | P09874 | 7/20 | 0.58 |
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.58 |
| ▸ | TDP2 | O95551 | 1/20 | 0.58 |
| ▸ | PARP11 | Q9NR21 | 6/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20894239 | 1.00 | PARP10 (0.58) | PARP10PARP1F7F3TDP2 | |
| Isophthalic Acid SCHEMBL28032858 | 0.94 | PARP10 (0.53) | PARP10PARP1F7F3TDP2 | |
| SCHEMBL30337030 | 0.87 | PARP11 (0.58) | PARP10PARP1TDP2PARP11PDPK1 | |
| SCHEMBL1417726 | 0.87 | PARP11 (0.58) | PARP10PARP1TDP2PARP11PDPK1 | |
| SCHEMBL14395011 | 0.85 | PARP10 (0.61) | PARP10PARP1F7F3TDP2 | |
| SCHEMBL30420500 | 0.85 | PARP10 (0.57) | PARP10PARP1F7F3TDP2 | |
| SCHEMBL5879567 | 0.83 | TDP2 (0.61) | TDP2KDM4EMAPTALDH1A1F11 | |
| SCHEMBL14395236 | 0.81 | PARP10 (0.56) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL12663981 | 0.81 | PARP10 (0.56) | PARP10PARP1F7F3TDP2 | |
| SCHEMBL8163134 | 0.81 | PARP10 (0.59) | PARP10PARP1F7F3TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |