Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 10/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | PRKACB | P22694 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 5/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417726 | 0.85 | PARP11 (0.58) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL30337030 | 0.85 | PARP11 (0.58) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL1727165 | 0.79 | PARP11 (0.72) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL30336933 | 0.75 | PRKACA (0.58) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL12683051 | 0.75 | PRKACA (0.58) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL29631237 | 0.74 | PARP10 (0.58) | PARP11PARP10SRD5A1SRD5A2KDM4E | |
| SCHEMBL20894239 | 0.74 | PARP10 (0.58) | PARP11PARP10SRD5A1SRD5A2KDM4E | |
| SCHEMBL31351705 | 0.74 | PARP11 (0.49) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL30421037 | 0.73 | PARP10 (0.57) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL29144306 | 0.72 | PARP11 (0.56) | PARP11PARP10PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618843-A | INHIBIT PLATELET AGGREGATION | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | disclosed |