Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223921 | 1.00 | MAPT (0.60) | MAPTRAB9AALDH1A1ARMAOB | |
| SCHEMBL29409544 | 0.84 | MAOB (0.68) | MAPTRAB9AALDH1A1MAOBMAOA | |
| SCHEMBL563933 | 0.84 | MAOB (0.68) | MAPTRAB9AALDH1A1MAOBMAOA | |
| SCHEMBL26777075 | 0.83 | MAOB (0.57) | MAPTRAB9AALDH1A1ARMAOB | |
| SCHEMBL2981516 | 0.81 | MAOB (0.74) | MAPTRAB9AALDH1A1ARMAOB | |
| SCHEMBL8346705 | 0.80 | MAOB (0.46) | MAPTRAB9AALDH1A1ARMAOB | |
| SCHEMBL29706440 | 0.80 | APP (0.55) | MAPTRAB9AARMEN1KMT2A | |
| SCHEMBL1143565 | 0.80 | APP (0.55) | MAPTRAB9AARMEN1KMT2A | |
| SCHEMBL8019602 | 0.78 | MAOA (0.60) | MAPTRAB9AALDH1A1ARMAOB | |
| SCHEMBL5539912 | 0.78 | HSD17B10 (0.45) | MAPTRAB9AALDH1A1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991688-A | Heterocyclic orange ketone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-04-21 | — | — | CN | disclosed |