SCHEMBL563933

SCHEMBL563933

O=C1COc2cc(O)ccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.68
MAOA P21397 3/20 0.68
MIF P14174 2/20 0.55
CYP19A1 P11511 4/20 0.54
ESR2 Q92731 2/20 0.54
TUBB4A P04350 1/20 0.54
TUBB P07437 1/20 0.54
YES1 P07947 1/20 0.54
TUBA3C P0DPH7 1/20 0.54
TUBA1B P68363 1/20 0.54
TUBA4A P68366 1/20 0.54
TUBB4B P68371 1/20 0.54
TUBB3 Q13509 1/20 0.54
TUBB2A Q13885 1/20 0.54
TUBB8 Q3ZCM7 1/20 0.54
TUBA3E Q6PEY2 1/20 0.54
TUBA1A Q71U36 1/20 0.54
TUBA1C Q9BQE3 1/20 0.54
TUBB6 Q9BUF5 1/20 0.54
TUBB2B Q9BVA1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29409544 1.00 MAOB (0.68) MAOBMAOAMIFCYP19A1ESR2
SCHEMBL26777075 0.91 MAOB (0.57) MAOBMAOAMIFCYP19A1ESR2
SCHEMBL30337075 0.84 MAPT (0.60) MAOBMAOAMIFESR2ALDH1A1
SCHEMBL3223921 0.84 MAPT (0.60) MAOBMAOAMIFESR2ALDH1A1
SCHEMBL30251430 0.81 MAOB (1.00) MAOBMAOACYP19A1ESR2TUBB4A
SCHEMBL1091999 0.81 MAOB (1.00) MAOBMAOACYP19A1ESR2TUBB4A
SCHEMBL8346705 0.80 MAOB (0.46) MAOBMAOAMIFCYP19A1ESR2
SCHEMBL26767781 0.80 MAOB (0.46) MAOBMAOAMIFCYP19A1ESR2
Water SCHEMBL15676351 0.79 MAOB (0.96) MAOBMAOACYP19A1ESR2TUBB4A
SCHEMBL6208215 0.79 ESR2 (0.58) MAOBMAOAMIFCYP19A1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192107-A Quenching fluorescent probe for specifically detecting gold ions and preparation method and application thereof 南京林业大学 2024-12-27 CN claimed
CN-119192105-A Process for the preparation of 6-benzofuranols 安徽昊帆生物有限公司 2024-12-27 CN claimed
CN-118852140-A Novel camphoryl fluorescent probe for detecting organophosphorus pesticide dimethoate as well as preparation method and application thereof 南京林业大学 2024-10-29 CN claimed
CN-113583320-A Crosslinkable polyolefin composition, preparation method and application thereof, crosslinked polyolefin and application thereof 国家能源投资集团有限责任公司 2021-11-02 CN claimed
US-20060228313-A1 Method of cosmetic depigmentation care by applying at least one aurone COLETICA (FR) 2006-10-12 US claimed
EP-1709964-A2 A method of cosmetic depigmentation care by applying at least one aurone ENGELHARD LYON (FR) 2006-10-11 EP claimed
CN-119060024-B Aryl benzyl ether compound with affinity with monoamine oxidase B and application thereof BEIJING NORMAL UNIVERSITY (CN) 2026-05-26 CN disclosed
US-20260132270-A1 FLUORORUBBER COMPOSITION AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2026-05-14 US disclosed
EP-4733355-A1 FLUORORUBBER COMPOSITION AND MOLDED ARTICLE Daikin Industries, Ltd. (JP) 2026-04-29 EP disclosed
EP-4680226-A2 ACYLSULFONAMIDE KAT6A INHIBITORS Olema Pharmaceuticals, Inc. (US) 2026-01-21 EP disclosed
US-20260015327-A1 ACYLSULFONAMIDE KAT6A INHIBITORS OLEMA PHARMACEUTICALS INC (US) 2026-01-15 US disclosed
EP-4658647-A1 TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS UCB Biopharma SRL (BE) 2025-12-10 EP disclosed
CN-118852140-B Camphor-based fluorescent probe for detecting organophosphorus pesticide dimethoate, and preparation method and application thereof 南京林业大学 2025-09-26 CN disclosed
US-4780480-A ANALGESICS, ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1988-10-25 US disclosed
US-4704390-A SCHIZOPHRENIA WARNER-LAMBERT COMPANY (US) 1987-11-03 US disclosed
EP-0237781-A2 Phenyl and heterocyclic tetrahydropyridyl and piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents WARNER-LAMBERT COMPANY (US) 1987-09-23 EP disclosed
EP-0132130-A2 Aroyl benzofuran and benzothiophene acetic and propionic acids processes for their production and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-23 EP disclosed
US-4486442-A ANTIANAPHYLACTIC BOEHRINGER MANNHEIM GMBH (DE) 1984-12-04 US disclosed
US-4083952-A Substituted aurones SMITHKLINE CORPORATION (US) 1978-04-11 US disclosed
US-3975380-A Substituted aurones SMITHKLINE CORPORATION (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060228313-A1 Method of cosmetic depigmentation care by applying at least one aurone TYR, MITF, MC1R MAOB 27/4885MAOA 23/4885MIF 3696/4885
US-20260015327-A1 ACYLSULFONAMIDE KAT6A INHIBITORS KAT6A, KAT2A, KAT6B MAOB 1290/4885MAOA 995/4885MIF 4666/4885
US-20260132270-A1 FLUORORUBBER COMPOSITION AND MOLDED ARTICLE FBP1, OGDH, ACACB MAOB 115/4885MAOA 306/4885MIF 3635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.