Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972569 | 1.00 | GAA (0.45) | GAACFTRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL11222239 | 0.87 | GAA (0.51) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14666358 | 0.83 | CFTR (0.53) | GAACFTRLMNAABL1HPGD | |
| SCHEMBL21857249 | 0.82 | GAA (0.50) | GAACFTRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL2849661 | 0.80 | CFTR (0.45) | GAACFTRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL852879 | 0.80 | GAA (0.51) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11308122 | 0.79 | GAA (0.66) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL30337032 | 0.79 | LCK (0.47) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3681759 | 0.79 | LCK (0.47) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL70011 | 0.79 | GAA (0.58) | GAASMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819398-B | Key intermediate of SGLT2 inhibitor, and preparation method and application thereof | 江苏联环药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115819398-A | SGLT2 inhibitor key intermediate and preparation method and application thereof | 江苏联环药业股份有限公司 | 2023-03-21 | — | — | CN | disclosed |