SCHEMBL2849661

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21857249	0.90	GAA (0.50)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL71501	0.86	GAA (0.52)	GAAABL1MEN1KMT2ALMNA
	SCHEMBL12488367	0.85	CFTR (0.43)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL17239556	0.85	CFTR (0.43)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL7948445	0.85	NR4A2 (0.46)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL7082612	0.84	GAA (0.46)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL22836884	0.84	CFTR (0.45)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL16117940	0.84	GAA (0.61)	GAAMEN1KMT2ALMNASMN1; SMN2
	SCHEMBL8331820	0.84	GAA (0.53)	CFTRGAAABL1MEN1KMT2A
	SCHEMBL857214	0.84	CFTR (0.60)	CFTRGAAABL1NR4A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.