Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198949 | 1.00 | ESR1 (0.41) | ESR1ESR2ARPGRLMNA | |
| SCHEMBL23198935 | 0.99 | ESR1 (0.42) | ESR1ESR2ARPGRLMNA | |
| SCHEMBL30337375 | 0.99 | ESR1 (0.42) | ESR1ESR2ARPGRLMNA | |
| SCHEMBL23198956 | 0.99 | ESR1 (0.42) | ESR1ESR2ARPGRLMNA | |
| SCHEMBL9354162 | 0.76 | NPSR1 (0.55) | ARPGRLMNANPSR1ALDH1A1 | |
| SCHEMBL23961109 | 0.75 | AR (0.37) | ARPGRLMNANPSR1ALDH1A1 | |
| SCHEMBL23198950 | 0.75 | AR (0.37) | ARPGRLMNANPSR1ALDH1A1 | |
| SCHEMBL31476409 | 0.73 | PGR (0.41) | ARPGRLMNANPSR1ALDH1A1 | |
| SCHEMBL3485083 | 0.73 | ALDH1A1 (0.41) | ESR1ESR2ARPGRLMNA | |
| SCHEMBL31476446 | 0.72 | AR (0.40) | ARPGRLMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11920040-B2 | Carborhodamine compounds and methods of preparation thereof | ELITECHGROUP MDX LLC (US) | 2024-03-05 | — | — | US | disclosed |
| US-20230105320-A1 | CARBORHODAMINE COMPOUNDS AND METHODS OF PREPARATION THEREOF | ELITECHGROUP MDX LLC (US) | 2023-04-06 | — | — | US | disclosed |
| US-11618826-B2 | Carborhodamine compounds and methods of preparation thereof | ELITECHGROUP MDX LLC (US) | 2023-04-04 | — | — | US | disclosed |