Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17542577 | 1.00 | EGFR (0.43) | EGFRDYRK1APGRSCN9AGSK3B | |
| SCHEMBL30337162 | 0.83 | DYRK1A (0.46) | EGFRDYRK1ASCN9AGSK3BJAK2 | |
| SCHEMBL28384419 | 0.83 | DYRK1A (0.46) | EGFRDYRK1ASCN9AGSK3BJAK2 | |
| SCHEMBL20610618 | 0.83 | GRM5 (0.37) | EGFRDYRK1AGSK3BMAP3K14CDK2 | |
| SCHEMBL30337212 | 0.82 | DYRK1A (0.45) | EGFRDYRK1ASCN9AGSK3BDYRK1B | |
| SCHEMBL19254846 | 0.82 | DYRK1A (0.45) | EGFRDYRK1ASCN9AGSK3BDYRK1B | |
| SCHEMBL17490471 | 0.82 | DYRK1A (0.45) | EGFRDYRK1ASCN9AGSK3BAURKA | |
| SCHEMBL17683321 | 0.81 | DYRK1A (0.44) | EGFRDYRK1ASCN9AGSK3BIGF1R | |
| SCHEMBL30459718 | 0.81 | DYRK1A (0.44) | EGFRDYRK1ASCN9AGSK3BIGF1R | |
| SCHEMBL28987593 | 0.79 | DYRK1A (0.44) | EGFRDYRK1ASCN9AGSK3BIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |