Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997197 | 1.00 | LMNA (0.50) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL30345059 | 1.00 | LMNA (0.50) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL30336795 | 0.96 | LMNA (0.46) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL30336892 | 0.82 | LMNA (0.58) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL23997318 | 0.82 | LMNA (0.58) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL25719533 | 0.81 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3591401 | 0.80 | MEN1 (0.55) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL23997192 | 0.80 | LMNA (0.53) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL30336805 | 0.80 | LMNA (0.53) | LMNAHTTMEN1CYP1A2KMT2A | |
| SCHEMBL23997452 | 0.78 | HDAC1 (0.45) | LMNAHTTMEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146644-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2023-03-15 | — | — | EP | disclosed |