Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405154 | 0.80 | USP2 (0.40) | CTSKUSP2SMN1; SMN2KDM1AUCHL1 | |
| SCHEMBL7405157 | 0.80 | USP2 (0.40) | CTSKUSP2SMN1; SMN2KDM1AUCHL1 | |
| SCHEMBL99227 | 0.75 | GRM5 (0.53) | CTSKUSP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28973059 | 0.74 | CTSK (0.38) | CTSKUSP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL18572758 | 0.74 | USP2 (0.35) | CTSKUSP2SMN1; SMN2KDM1AUCHL1 | |
| SCHEMBL30803371 | 0.73 | ESR2 (0.46) | CTSKUSP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14954612 | 0.73 | ESR2 (0.46) | CTSKUSP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2558056 | 0.73 | ESR2 (0.46) | CTSKUSP2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31715308 | 0.72 | USP2 (0.39) | CTSKUSP2SMN1; SMN2KDM1AMEN1 | |
| SCHEMBL344121 | 0.71 | USP2 (0.41) | CTSKUSP2SMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317946-A | Processes and intermediates for the preparation of baratinib | 因赛特公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-115836065-A | Methods of making JAK1 inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |