Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12350366 | 0.84 | CTSK (0.38) | USP2SMN1; SMN2CTSKHPGDMEN1 | |
| SCHEMBL30002394 | 0.82 | HPGD (0.37) | USP2SMN1; SMN2CTSKHPGDMEN1 | |
| SCHEMBL463899 | 0.82 | CTSK (0.36) | USP2SMN1; SMN2CTSKHPGDMEN1 | |
| SCHEMBL463898 | 0.82 | CTSK (0.36) | USP2SMN1; SMN2CTSKHPGDMEN1 | |
| SCHEMBL21348242 | 0.80 | USP2 (0.34) | USP2SMN1; SMN2CTSKHPGDUCHL1 | |
| SCHEMBL31322461 | 0.80 | CTSK (0.40) | USP2SMN1; SMN2CTSKHPGDMEN1 | |
| SCHEMBL1550544 | 0.79 | USP2 (0.41) | USP2SMN1; SMN2CTSKHPGDUCHL1 | |
| SCHEMBL15188491 | 0.79 | CTSK (0.44) | USP2SMN1; SMN2CTSKHPGDUCHL1 | |
| SCHEMBL205421 | 0.79 | LMNA (0.48) | USP2SMN1; SMN2CTSKHPGDMEN1 | |
| SCHEMBL31357623 | 0.79 | HDAC1 (0.36) | USP2SMN1; SMN2CTSKHPGDUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025184391-A9 | COVALENT INHIBITORS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2025-10-30 | — | — | WO | disclosed |