Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238381 | 0.88 | ACHE (0.67) | ACHEL3MBTL1JAK2JAK1MKNK1 | |
| SCHEMBL22399206 | 0.77 | ACHE (0.68) | ACHEL3MBTL1JAK2JAK1MKNK1 | |
| SCHEMBL22393858 | 0.75 | L3MBTL1 (0.49) | ACHEL3MBTL1MEN1KMT2A | |
| SCHEMBL19159430 | 0.75 | ACHE (0.40) | ACHEJAK2JAK1 | |
| SCHEMBL24853044 | 0.74 | ACHE (0.54) | ACHETLR8L3MBTL1 | |
| SCHEMBL22326800 | 0.74 | ACHE (0.46) | ACHETLR8L3MBTL1MKNK1MKNK2 | |
| SCHEMBL6233599 | 0.73 | ACHE (0.63) | ACHEMEN1KMT2A | |
| SCHEMBL29399366 | 0.72 | ACHE (0.54) | ACHEL3MBTL1JAK2JAK1MKNK1 | |
| SCHEMBL28309802 | 0.72 | ACHE (0.49) | ACHEMKNK1MKNK2 | |
| SCHEMBL25819849 | 0.72 | ACHE (0.49) | ACHEMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916341-A | Pyrazole carboxamide compounds for the treatment of HBV | 组装生物科学股份有限公司 | 2023-04-04 | — | — | CN | disclosed |