Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25125923 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL23483339 | 0.99 | ALDH1A1 (0.45) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL24002897 | 0.97 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL23845983 | 0.97 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL23483444 | 0.95 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL24003188 | 0.95 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL23461761 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL23483280 | 0.94 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL23483445 | 0.94 | ALDH1A1 (0.40) | ALDH1A1KMT2APOLBLMNAPRKCA | |
| SCHEMBL24771055 | 0.93 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250268828-A1 | Lipid Nanoparticle Compositions for Delivering Circular Polynucleotides | ORNA THERAPEUTICS, INC. | 2025-08-28 | — | — | US | disclosed |
| EP-4408825-A1 | LIPID NANOPARTICLE COMPOSITIONS FOR DELIVERING CIRCULAR POLYNUCLEOTIDES | Orna Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023056033-A1 | LIPID NANOPARTICLE COMPOSITIONS FOR DELIVERING CIRCULAR POLYNUCLEOTIDES | ORNA THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250268828-A1 | Lipid Nanoparticle Compositions for Delivering Circular Polynucleotides | ABCB4, CETP, HDLBP | ALDH1A1 4651/4885KMT2A 3198/4885POLB 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.