Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875063 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL1882890 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29823331 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4428290 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL14931741 | 0.78 | KMT2A (0.68) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL30225577 | 0.78 | KMT2A (0.68) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13016958 | 0.78 | MAPT (0.63) | KMT2AL3MBTL1SMN1; SMN2MAPTLIN28A | |
| SCHEMBL6781182 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL22305532 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL21975726 | 0.72 | KMT2A (0.60) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115997009-A | Methods and compositions for in vivo transduction of hematopoietic stem and progenitor cells | 美真达治疗公司 | 2023-04-21 | — | — | CN | disclosed |