Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904435 | 0.78 | KMT2A (0.68) | DHFRALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL27542221 | 0.74 | PLAU (0.58) | ALDH1A1HPGDHSD17B10CYP3A4TP53 | |
| SCHEMBL6305612 | 0.72 | MAPK8 (0.52) | DHFRALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL27420834 | 0.71 | SMN1; SMN2 (0.55) | DHFRALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL11806850 | 0.71 | HSD17B10 (0.49) | DHFRALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL49213 | 0.71 | HSD17B10 (0.74) | ALDH1A1HPGDHSD17B10CYP3A4TP53 | |
| SCHEMBL15223284 | 0.71 | NCF1 (0.53) | ALDH1A1HPGDHSD17B10CYP3A4TP53 | |
| SCHEMBL1602180 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL6796333 | 0.70 | EGFR (0.51) | DHFRALDH1A1HPGDHSD17B10CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL11586421 | 0.69 | HSD17B10 (0.71) | ALDH1A1HPGDHSD17B10CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115997009-A | Methods and compositions for in vivo transduction of hematopoietic stem and progenitor cells | 美真达治疗公司 | 2023-04-21 | — | — | CN | disclosed |