Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3385235 | 1.00 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL30235018 | 0.98 | HTR2A (0.41) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| Bromide SCHEMBL3382945 | 0.95 | HTR2A (0.45) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| Fluoride Ion SCHEMBL3381995 | 0.95 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| Iodide SCHEMBL3382686 | 0.95 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL30573465 | 0.73 | HTR2A (0.41) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL8373144 | 0.73 | HTR2A (0.41) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL1436674 | 0.73 | HTR2A (0.41) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL5698322 | 0.72 | HTR2A (0.44) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL8070813 | 0.71 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132161-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORP (CN) | 2026-05-14 | — | — | US | claimed |
| EP-4603495-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-08-20 | — | — | EP | claimed |
| CN-117903216-A | Phosphine-phenol single metallocene complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| WO-2024078525-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国石油化工股份有限公司 | 2024-04-18 | — | — | WO | claimed |
| CN-115894758-A | Ethylene-cycloolefin copolymer and method for producing the same | 中国石油化工股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| US-20260132161-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORP (CN) | 2026-05-14 | — | — | US | disclosed |
| EP-4603495-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-08-20 | — | — | EP | disclosed |
| CN-119798492-A | Coordination precipitation polymerization process for olefin polymerization and polyolefin | 中国石油化工股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119661751-A | Coordination precipitation polymerization process for olefin polymerization and polyolefin | 中国石油化工股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-118047991-A | Elastomer composition, elastic article and method of making the same | 中国石油天然气股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-118047892-A | Ethylene and alpha-olefin copolymer, and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-118005832-A | Ethylene, alpha-olefin and isolated diene copolymer, and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005833-A | Ethylene, alpha-olefin and isolated diene copolymer, and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117903216-A | Phosphine-phenol single metallocene complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2024078525-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国石油化工股份有限公司 | 2024-04-18 | — | — | WO | disclosed |
| CN-116789880-A | Phosphazene single-metallocene catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132161-A1 | PHOSPHINE-PHENOL HALF-METALLOCENE COMPLEX, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4A11, CYP4F11, FAR1 | CHRM2 2902/4885CHRM1 1633/4885CHRM3 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.