Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352714 | 0.84 | HTR2A (0.38) | HTR2AHTR6KDM4ECYP2D6TP53 | |
| Hydrochloric Acid SCHEMBL1538888 | 0.82 | HTR6 (0.40) | HTR2AHTR6KDM4ECYP2D6TP53 | |
| SCHEMBL5823608 | 0.82 | CYP2D6 (0.39) | HTR2AHTR6KDM4ECYP2D6TP53 | |
| SCHEMBL7302548 | 0.80 | HTR6 (0.33) | HTR2AHTR6RET | |
| SCHEMBL28839778 | 0.80 | HTR2A (0.35) | HTR2AHTR6KDM4ECYP2D6ALDH1A1 | |
| SCHEMBL7185802 | 0.80 | HTR2A (0.35) | HTR2AHTR6KDM4ECYP2D6MEN1 | |
| SCHEMBL1074094 | 0.80 | HTR2A (0.35) | HTR2AHTR6KDM4ECYP2D6HTR2C | |
| SCHEMBL7185808 | 0.80 | HTR2A (0.35) | HTR2AHTR6KDM4ECYP2D6MEN1 | |
| SCHEMBL10589173 | 0.79 | PRCP (0.38) | HTR2AHTR6KDM4ECYP2D6HTR2C | |
| SCHEMBL7605148 | 0.79 | PRCP (0.38) | HTR2AHTR6KDM4ECYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250342-B1 | BRIDGED METALLOCENE COMPOUNDS AS OLEFIN-POLYMERIZATION CATALYSTS | POLIMERI EUROPA SPA (IT) | 2006-06-28 | — | — | EP | disclosed |
| US-6984703-B1 | Bridged metallocene compounds as olefin-polymerization catalysts | POLIMERI EUROPA S.P.A. (IT) | 2006-01-10 | — | — | US | disclosed |
| EP-0716092-B1 | Organic transition metal compound and process for the preparation of polyolefin using same | TOSOH CORP (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-5770666-A | METALLOCENE | TOSOH CORPORATION (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0716092-A1 | Organic transition metal compound and process for the preparation of polyolefin using same | TOSOH CORPORATION (JP) | 1996-06-12 | — | — | EP | disclosed |
| EP-0236488-A1 | HELICAL METALLOCENE OLIGOMERS AND A METHOD FOR THEIR PREPARATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1987-09-16 | — | — | EP | disclosed |
| WO-1987001704-A1 | HELICAL METALLOCENE OLIGOMERS AND A METHOD FOR THEIR PREPARATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 1987-03-26 | — | — | WO | disclosed |