Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30338653

Cc1cc([C@@H]2CCON2)co1.O=C(O)C(F)(F)F

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29048329 1.00 KDM1A (0.32) KDM1ACHRNA4
Trifluoroacetic Acid SCHEMBL30455502 0.78 KDM1A (0.34) KDM1A
Trifluoroacetic Acid SCHEMBL29048254 0.75 GPR6 (0.33) KDM1ACHRNA4
Trifluoroacetic Acid SCHEMBL31205908 0.75 ABL1 (0.32) CHRNA4
Trifluoroacetic Acid SCHEMBL30338646 0.74 CHRNB2 (0.33) KDM1ACHRNA4
Trifluoroacetic Acid SCHEMBL25297194 0.74 POLB (0.34) KDM1A
Trifluoroacetic Acid SCHEMBL30581170 0.73 CHRNB2 (0.33) KDM1ACHRNA4
Trifluoroacetic Acid SCHEMBL30339079 0.73 CHRNB2 (0.33) KDM1ACHRNA4
Trifluoroacetic Acid SCHEMBL30338672 0.73 CHRNB2 (0.33) KDM1ACHRNA4
Trifluoroacetic Acid SCHEMBL31205907 0.73 HDAC4 (0.37) CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4157835-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF SANOFI (FR) 2023-04-05 EP disclosed