Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13362350 | 1.00 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP17A1CYP19A1ABCB1 | |
| SCHEMBL30338584 | 0.88 | CYP11B2 (0.65) | CYP11B2CYP11B1CYP17A1CYP19A1ABCB1 | |
| SCHEMBL9009066 | 0.82 | CYP2A6 (0.65) | CYP11B2CYP11B1CYP17A1CYP19A1CYP3A4 | |
| SCHEMBL27859257 | 0.80 | CYP1A1 (0.55) | CYP11B2CYP11B1CYP17A1ABCB1CYP1A1 | |
| SCHEMBL30018135 | 0.80 | CYP1A1 (0.55) | CYP11B2CYP11B1CYP17A1ABCB1CYP1A1 | |
| SCHEMBL29566706 | 0.80 | CYP11B2 (0.73) | CYP11B2CYP11B1CYP17A1CYP19A1CYP3A4 | |
| SCHEMBL792083 | 0.80 | CYP11B2 (0.73) | CYP11B2CYP11B1CYP17A1CYP19A1CYP3A4 | |
| SCHEMBL29419006 | 0.80 | CYP11B2 (0.63) | CYP11B2CYP11B1CYP17A1CYP19A1CYP1A1 | |
| SCHEMBL6606854 | 0.79 | CYP1A1 (0.55) | ABCB1CYP1A1CYP1B1CYP3A4CYP1A2 | |
| SCHEMBL30255126 | 0.78 | CYP2A6 (0.54) | CYP11B2CYP11B1CYP3A4CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230086703-A1 | N-(4-(5-chloropyridin-3-yl)phenyl)-2-(2-(cyclopropanesulfonamido)pyrimidin-4-yl) butanamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | STEP PHARMA S.A.S. (FR) | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230086703-A1 | N-(4-(5-chloropyridin-3-yl)phenyl)-2-(2-(cyclopropanesulfonamido)pyrimidin-4-yl) butanamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | CTPS1, CTPS2, CERS2 | CYP11B2 2350/4885CYP11B1 1632/4885CYP17A1 2801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.