Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074254 | 1.00 | MAPT (0.44) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL24074156 | 0.93 | TDP1 (0.43) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL30339231 | 0.93 | TDP1 (0.43) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL24074193 | 0.89 | TDP1 (0.58) | MAPTTDP1GAAPDE4BTRPV1 | |
| SCHEMBL25063316 | 0.84 | KDM4E (0.49) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL24072612 | 0.82 | TDP1 (0.56) | MAPTTDP1PDE4BTRPV1TP53 | |
| SCHEMBL13634634 | 0.77 | PRMT5 (0.48) | KDM4EGAAPTPN1TSHR | |
| SCHEMBL27589069 | 0.77 | TDP1 (0.61) | MAPTTDP1ALDH1A1GAATSHR | |
| SCHEMBL24072264 | 0.77 | HCAR1 (0.39) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL12316328 | 0.76 | GAA (0.45) | TDP1KDM4EALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |