Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25063316 | 0.78 | KDM4E (0.49) | PRMT5WDR77PTPN1PTGS1PTGS2 | |
| SCHEMBL24074254 | 0.77 | MAPT (0.44) | PTPN1KDM4EGAATSHR | |
| SCHEMBL30338987 | 0.77 | MAPT (0.44) | PTPN1KDM4EGAATSHR | |
| SCHEMBL171233 | 0.76 | BACE1 (0.46) | PRMT5WDR77PTGS1PTGS2MAPK1 | |
| SCHEMBL17308602 | 0.76 | RAPGEF4 (0.46) | MAPK1TSHRPOLB | |
| SCHEMBL6120734 | 0.75 | TDP1 (0.49) | TSHR | |
| SCHEMBL30258360 | 0.74 | ALDH1A1 (0.63) | PTPN1RIPK2MAPK1 | |
| SCHEMBL15830060 | 0.73 | BACE1 (0.48) | PRMT5WDR77PTGS1PTGS2MAPK1 | |
| SCHEMBL23269826 | 0.72 | HCAR3 (0.40) | MAPK1KDM4EGAATSHR | |
| SCHEMBL20129698 | 0.71 | MTOR (0.49) | KDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |