Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 6/20 | 0.46 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340548 | 0.90 | MAPK10 (0.51) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340587 | 0.84 | CDK2 (0.55) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340656 | 0.84 | IGF1R (0.53) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340490 | 0.81 | MAPK10 (0.52) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340650 | 0.81 | EGFR (0.53) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340630 | 0.80 | MAPK10 (0.51) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340493 | 0.80 | IGF1R (0.54) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340504 | 0.79 | MAPK10 (0.51) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340484 | 0.79 | CDK2 (0.56) | MAPK10EGFRIGF1RCDK2DYRK1B | |
| SCHEMBL30340737 | 0.79 | MAPK10 (0.51) | MAPK10EGFRIGF1RCDK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4402127-A1 | AMINOPYRIDINES AS ACTIVATORS OF PI3 KINASE | UCL Business Ltd (GB) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023041905-A1 | AMINOPYRIDINES AS ACTIVATORS OF PI3 KINASE | UCL BUSINESS LTD (GB) | 2023-03-23 | — | — | WO | disclosed |