Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446076 | 0.78 | CES2 (0.36) | — | |
| SCHEMBL1445753 | 0.74 | CES2 (0.30) | — | |
| SCHEMBL38662699 | 0.73 | HDAC4 (0.30) | — | |
| SCHEMBL31444326 | 0.73 | TAAR1 (0.32) | — | |
| SCHEMBL1863530 | 0.73 | TAAR1 (0.32) | — | |
| SCHEMBL31289362 | 0.72 | TNF (0.41) | TNFRIPK1 | |
| SCHEMBL2046247 | 0.72 | TNF (0.41) | TNFRIPK1 | |
| SCHEMBL1003501 | 0.69 | TNF (0.35) | TNFRIPK1 | |
| SCHEMBL29414007 | 0.69 | TNF (0.35) | TNFRIPK1 | |
| SCHEMBL4659546 | 0.68 | SLC6A4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881664-A | Cycloalkyl 3-oxopiperazine carboxamides and cycloheteroalkyl 3-oxopiperazine carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| EP-4168393-A1 | 2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-04-26 | — | — | EP | disclosed |