SCHEMBL1445753

SCHEMBL1445753

Fc1ccc([Mg]Br)c(F)c1F.Fc1ccc([Mg]Cl)c(F)c1F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446076 0.89 CES2 (0.36) CES2CES1
SCHEMBL30342140 0.74 TNF (0.32)
SCHEMBL38662699 0.70 HDAC4 (0.30)
SCHEMBL1162776 0.69 CES2 (0.38) CES2CES1
SCHEMBL31444457 0.69 CES2 (0.38) CES2CES1
SCHEMBL1445913 0.69 CES2 (0.38) CES2CES1
Bromide SCHEMBL1445880 0.66 CES2 (0.36) CES2CES1
SCHEMBL1445878 0.66
SCHEMBL29489580 0.65 CES2 (0.53) CES2CES1
SCHEMBL45430 0.65 CES2 (0.53) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8609574-B2 In situ olefin polymerization catalyst system PROMERUS LLC (US) 2013-12-17 US disclosed
EP-2296811-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM Promerus, LLC (US) 2011-03-23 EP disclosed
US-20090270247-A1 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 US disclosed
WO-2009132240-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 WO disclosed