Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981927 | 0.79 | DRD1 (0.44) | — | |
| SCHEMBL29005250 | 0.76 | — | — | |
| SCHEMBL29005200 | 0.75 | DAO (0.40) | — | |
| SCHEMBL19753970 | 0.72 | RXRA (0.46) | RXRAGRIN1GRIN2B | |
| SCHEMBL20582207 | 0.71 | RXRA (0.38) | RXRAGRIN1GRIN2B | |
| SCHEMBL12492551 | 0.71 | RXRA (0.38) | RXRAGRIN1GRIN2B | |
| SCHEMBL16478700 | 0.71 | GRIN1 (0.42) | RXRAGRIN1GRIN2B | |
| SCHEMBL7995989 | 0.71 | DAO (0.33) | RXRAGRIN1GRIN2B | |
| SCHEMBL14800933 | 0.70 | SYK (0.46) | — | |
| Hydrochloric Acid SCHEMBL30345248 | 0.69 | RXRA (0.32) | RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| EP-4168393-A1 | 2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-04-26 | — | — | EP | disclosed |