Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416918 | 0.81 | ALDH1A1 (0.54) | DAONPC1ALDH1A1L3MBTL1DRD1 | |
| SCHEMBL7999562 | 0.81 | ALDH1A1 (0.54) | DAONPC1ALDH1A1L3MBTL1DRD1 | |
| SCHEMBL30342175 | 0.75 | RXRA (0.31) | — | |
| SCHEMBL998514 | 0.75 | TUBB4A (0.53) | NPC1ALDH1A1KDM4ETUBB4ATUBB | |
| SCHEMBL9838960 | 0.75 | DAO (0.39) | DAONPC1ALDH1A1KDM4EHCRTR1 | |
| SCHEMBL23906743 | 0.74 | DAO (0.35) | DAONPC1ALDH1A1L3MBTL1POLB | |
| SCHEMBL15941773 | 0.74 | P4HTM (0.54) | NPC1ALDH1A1KDM4EPOLBRAB9A | |
| SCHEMBL15941772 | 0.74 | P4HTM (0.54) | NPC1ALDH1A1KDM4EPOLBRAB9A | |
| SCHEMBL2718833 | 0.73 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1POLBAPPMAPT | |
| SCHEMBL28469332 | 0.73 | GABRP (0.40) | NPC1ALDH1A1KDM4ETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |