⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728560 | 0.76 | — | — | |
| SCHEMBL15647364 | 0.76 | — | — | |
| SCHEMBL15647930 | 0.76 | — | — | |
| SCHEMBL5656849 | 0.70 | — | — | |
| SCHEMBL1447713 | 0.68 | — | — | |
| SCHEMBL15641746 | 0.65 | NOS3 (0.33) | — | |
| SCHEMBL15184 | 0.65 | — | — | |
| SCHEMBL554737 | 0.65 | — | — | |
| SCHEMBL18643888 | 0.63 | NOS3 (0.32) | — | |
| SCHEMBL22068846 | 0.63 | NOS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4167994-A1 | 2-OXO-OXAZOLIDINE-5-CARBOXAMIDES AS NAV1.8 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| EP-4168393-A1 | 2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-04-26 | — | — | EP | disclosed |