SCHEMBL554737

SCHEMBL554737

FC(F)(F)C1CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15641746 0.92 NOS3 (0.33)
SCHEMBL15184 0.92
SCHEMBL59958 0.89 NOS3 (0.32)
SCHEMBL22068846 0.89 NOS3 (0.32)
SCHEMBL18643888 0.89 NOS3 (0.32)
SCHEMBL1035041 0.86 MITF (0.31)
Ammonia Solution, Strong SCHEMBL18669725 0.86 NOS3 (0.31)
SCHEMBL18060 0.84
SCHEMBL1035408 0.84 NOS3 (0.36)
SCHEMBL13742212 0.81 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 989 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119016006-A Gas-liquid reaction kettle and production method of perfluorinated resin 肖进新 2024-11-26 CN claimed
CN-115572339-B Ion modified perfluorinated anion resin and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2024-08-06 CN claimed
CN-118165587-A Fusible polytetrafluoroethylene coating, preparation method thereof and coated workpiece 福建海德福新材料有限公司 2024-06-11 CN claimed
US-20240109866-A1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. 2024-04-04 US claimed
WO-2023239768-A1 TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS INCYTE CORPORATION (US) 2023-12-14 WO claimed
WO-2023240024-A1 SULFAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS NIKANG THERAPEUTICS, INC. (US) 2023-12-14 WO claimed
US-20230399342-A1 TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS INCYTE CORPORATION 2023-12-14 US claimed
WO-2023192801-A1 SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS NIKANG THERAPEUTICS, INC. (US) 2023-10-05 WO claimed
US-20230303509-A1 SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS NIKANG THERAPEUTICS, INC. 2023-09-28 US claimed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP claimed
EP-0885317-B1 FLASH SPINNING PROCESS AND FLASH SPINNING SOLUTION DU PONT (US) 2000-08-09 EP claimed
WO-1997033016-A9 FLASH SPINNING PROCESS AND FLASH SPINNING SOLUTION 1998-10-29 WO claimed
US-5798091-A DISSOLVING A MICROSPHERES MADE OF TWO SURFACTANTS, FIRST ONE IS PHOSPHOLIPIDS AND SECOND, MORE WATER SOULBLE SURFACTANT, A HYDROPHILIC MONOMER OR POLYMER AND GAS MIXTURE TO AN AQUEOUS SOLUTION AND FORMING GAS EMULSION; ULTRASOUND IMAGING ALLIANCE PHARMACEUTICAL CORP. (US) 1998-08-25 US claimed
US-5720938-A CHAMBER CONTAINING VOID-CONTAINING STRUCTURES, FLUOROCARBON GAS OSMOTIC AGENT, SECOND CHAMBER CONTAINING AQUEOUS LIQUID, SURFACTANT, SEAL SEPARATING FIRST AND SECOND CHAMBERS; ULTRASOUND CONTRAST AGENT ALLIANCE PHARMACEUTICAL CORP. (US) 1998-02-24 US claimed
US-5695741-A Stable microbubble precursors ALLIANCE PHARMACEUTICAL CORP. (US) 1997-12-09 US claimed
US-5605673-A SURROUNDING A FIRST AND SECOND GAS WITH A MEMBRANE FORMING MATERIAL SUCH AS A SURFACTANT ALLIANCE PHARMACEUTICAL CORP. (US) 1997-02-25 US claimed
EP-0031708-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR ICI PHARMA (FR) 1984-06-13 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0071370-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them ICI PHARMA (FR) 1983-02-09 EP claimed
EP-0031708-A2 Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor ICI PHARMA (FR) 1981-07-08 EP claimed