SCHEMBL30342248

SCHEMBL30342248

O=C(CCl)Nc1ccc(F)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.64
NPSR1 Q6W5P4 1/20 0.57
POLB P06746 2/20 0.52
ALOX15 P16050 6/20 0.51
TDP1 Q9NUW8 2/20 0.51
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPT P10636 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
HTT P42858 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.48
PYGL P06737 1/20 0.47
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10951824 1.00 KMT2A (0.64) KMT2ANPSR1POLBALOX15TDP1
SCHEMBL31384714 0.85 KMT2A (0.62) KMT2ANPSR1POLBALOX15TDP1
SCHEMBL263278 0.84 RAB9A (0.59) KMT2APOLBTDP1ALDH1A1SMN1; SMN2
SCHEMBL30986310 0.84 RAB9A (0.59) KMT2APOLBTDP1ALDH1A1SMN1; SMN2
SCHEMBL1116467 0.83 NPSR1 (0.61) KMT2ANPSR1POLBALOX15TDP1
SCHEMBL9846829 0.83 HDAC3 (0.51) KMT2ANPSR1POLBTDP1ALDH1A1
SCHEMBL5858216 0.82 HPGD (0.62) KMT2APOLBALDH1A1SMN1; SMN2MAPT
SCHEMBL29678338 0.82 HPGD (0.62) KMT2APOLBALDH1A1SMN1; SMN2MAPT
SCHEMBL5913136 0.81 ALDH1A1 (0.51) KMT2ANPSR1POLBALDH1A1SMN1; SMN2
SCHEMBL29678316 0.81 ALDH1A1 (0.51) KMT2ANPSR1POLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111892511-B N- (2-chloro-4-fluorophenyl) -2- (2,4,6-trichlorophenoxy) acetamide and application thereof 青岛农业大学 2023-04-07 CN claimed
CN-118126030-A Preparation method of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative and application of pyrazoline-1, 3, 4-oxadiazole thioacetamide derivative as pesticide 贵州大学 2024-06-04 CN disclosed
CN-111892511-B N- (2-chloro-4-fluorophenyl) -2- (2,4,6-trichlorophenoxy) acetamide and application thereof 青岛农业大学 2023-04-07 CN disclosed
CN-111892511-B N- (2-chloro-4-fluorophenyl) -2- (2,4,6-trichlorophenoxy) acetamide and application thereof 青岛农业大学 2023-04-07 CN disclosed