SCHEMBL30343162

SCHEMBL30343162

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 3/20 0.66
▸ OPRM1 P35372 2/20 0.66
▸ CCKAR P32238 1/20 0.54
▸ CCKBR P32239 1/20 0.54
▸ ERAP1 Q9NZ08 2/20 0.51
▸ ERAP2 Q6P179 1/20 0.51
▸ LNPEP Q9UIQ6 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30414279 0.94 OPRM1 (0.58) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL30797170 0.93 OPRM1 (0.57) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL29577523 0.91 ERAP1 (0.56) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL29577107 0.91 ERAP1 (0.56) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL29619552 0.90 OPRM1 (0.54) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL7048052 0.90 ERAP1 (0.57) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL7936370 0.90 ERAP1 (0.57) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL7048050 0.90 ERAP1 (0.57) OPRD1OPRM1ERAP1ERAP2LNPEP
SCHEMBL29577130 0.88 LTA4H (0.57) ERAP1ERAP2
SCHEMBL29577979 0.88 LTA4H (0.57) ERAP1ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 OPRD1 3688/4885OPRM1 3068/4885CCKAR 3106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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