⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934023 | 0.77 | — | — | |
| SCHEMBL19359111 | 0.72 | — | — | |
| SCHEMBL19359107 | 0.71 | — | — | |
| SCHEMBL31247838 | 0.65 | — | — | |
| SCHEMBL25359893 | 0.61 | L3MBTL1 (0.47) | — | |
| SCHEMBL945086 | 0.61 | — | — | |
| SCHEMBL24428114 | 0.60 | ACHE (0.44) | — | |
| SCHEMBL24044949 | 0.59 | — | — | |
| SCHEMBL22388624 | 0.59 | — | — | |
| SCHEMBL1569997 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873000-B | Isoquinolinones and quinazolinones compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023051495-A1 | ISOQUINOLINONE AND QUINAZOLINONE COMPOUNDS, AND COMPOSITION AND USE THEREOF | 中山医诺维申新药研发有限公司 | 2023-04-06 | — | — | WO | disclosed |