Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11886365 | 0.85 | CYP2A6 (0.48) | CYP2A6KDM4ELMNAMETAP1CCR1 | |
| SCHEMBL56776 | 0.79 | KDM4E (0.56) | KDM4ELMNAMETAP1CCR1CCR5 | |
| SCHEMBL30161776 | 0.79 | KDM4E (0.56) | KDM4ELMNAMETAP1CCR1CCR5 | |
| SCHEMBL29466690 | 0.79 | KDM4E (0.56) | KDM4ELMNAMETAP1CCR1CCR5 | |
| SCHEMBL12854083 | 0.78 | KDM4E (0.50) | CYP2A6KDM4ELMNAMETAP1CCR1 | |
| SCHEMBL15485572 | 0.78 | KDM4E (0.54) | KDM4ELMNAMETAP1CCR1CCR5 | |
| SCHEMBL20591288 | 0.78 | KDM4E (0.54) | KDM4ELMNAMETAP1CCR1CCR5 | |
| SCHEMBL16820308 | 0.78 | KDM4E (0.54) | KDM4ELMNAMETAP1CCR1CCR5 | |
| SCHEMBL13215866 | 0.78 | CYP2A6 (0.43) | CYP2A6KDM4EMETAP1METAP2KDM1A | |
| SCHEMBL29985871 | 0.78 | KDM4E (0.54) | KDM4ELMNAMETAP1CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216818-A1 | Inhibitors of Post-Amadori Advanced Glycation End Products | KHALIFAH RAJA | 2010-08-26 | — | — | US | claimed |
| EP-1534679-A4 | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS | BIOSTRATUM INC (US) | 2007-06-06 | — | — | EP | claimed |
| EP-1534679-A2 | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS | Biostratum, Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| US-20040122061-A1 | Inhibitors of post-amadori advanced glycation end products | BIOSTRATUM, INC. | 2004-06-24 | — | — | US | claimed |
| WO-2004019889-A2 | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS | BIOSTRATUM, INC. (US) | 2004-03-11 | — | — | WO | claimed |
| US-11814401-B2 | Luminescent material and electroluminescent display device using the same | LG DISPLAY CO., LTD (KR) | 2023-11-14 | — | — | US | disclosed |
| US-11814401-B2 | Luminescent material and electroluminescent display device using the same | LG DISPLAY CO., LTD (KR) | 2023-11-14 | — | — | US | disclosed |
| US-8227093-B2 | Cyclometalated transition metal complex and organic electroluminescence device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2012-07-24 | — | — | US | disclosed |
| US-8227093-B2 | Cyclometalated transition metal complex and organic electroluminescence device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2012-07-24 | — | — | US | disclosed |
| US-8039123-B2 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2011-10-18 | — | — | US | disclosed |
| US-20100216818-A1 | Inhibitors of Post-Amadori Advanced Glycation End Products | KHALIFAH RAJA | 2010-08-26 | — | — | US | disclosed |
| US-20100216818-A1 | Inhibitors of Post-Amadori Advanced Glycation End Products | KHALIFAH RAJA | 2010-08-26 | — | — | US | disclosed |
| US-20070267959-A1 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-11-22 | — | — | US | disclosed |
| US-20070190358-A1 | Cyclometalated transition metal complex and organic electroluminescence device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-08-16 | — | — | US | disclosed |
| US-20070190358-A1 | Cyclometalated transition metal complex and organic electroluminescence device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-08-16 | — | — | US | disclosed |
| EP-1534679-A4 | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS | BIOSTRATUM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1534679-A2 | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS | Biostratum, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040122061-A1 | Inhibitors of post-amadori advanced glycation end products | BIOSTRATUM, INC. | 2004-06-24 | — | — | US | disclosed |
| WO-2004019889-A2 | INHIBITORS OF POST-AMADORI ADVANCED GLYCATION END PRODUCTS | BIOSTRATUM, INC. (US) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267959-A1 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | ORC3, AP3M1, PUF60 | CYP2A6 4766/4885KDM4E 3707/4885LMNA 3593/4885 |
| US-11814401-B2 | Luminescent material and electroluminescent display device using the same | ALDH1A2, CD99, EPB41L2 | CYP2A6 2994/4885KDM4E 2538/4885LMNA 3808/4885 |
| US-20100216818-A1 | Inhibitors of Post-Amadori Advanced Glycation End Products | AGER, GLA, OGA | CYP2A6 2813/4885KDM4E 2055/4885LMNA 708/4885 |
| US-20040122061-A1 | Inhibitors of post-amadori advanced glycation end products | AGER, GLA, OGA | CYP2A6 2813/4885KDM4E 2055/4885LMNA 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.