SCHEMBL30344009

SCHEMBL30344009

Fc1ccc2c(c1)C=CCC2

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.37
PARP1 P09874 1/20 0.34
PARP10 Q53GL7 1/20 0.34
ADRA2A P08913 1/20 0.34
SRD5A1 P18405 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
TXNRD1 Q16881 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ACHE P22303 1/20 0.31
HTR5A P47898 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7676238 0.83 FFAR4 (0.40) KDM1APARP1PARP10SRD5A1FFAR4
SCHEMBL2285134 0.78 PARP1 (0.36) KDM1APARP1PARP10ADRA2ASRD5A1
SCHEMBL17068939 0.78 ADRA2A (0.33) KDM1APARP1PARP10ADRA2AHTR2A
SCHEMBL819543 0.78 ADRA2A (0.33) KDM1APARP1PARP10ADRA2AHTR2A
SCHEMBL31503035 0.75 CA9 (0.35)
SCHEMBL2524442 0.75
SCHEMBL7650098 0.75 CA9 (0.35)
SCHEMBL13782128 0.75 ADRA2A (0.37) ADRA2A
SCHEMBL9114452 0.75 PARP10 (0.34) PARP1PARP10ACHEHTR5A
SCHEMBL29634842 0.75 PNMT (0.37) KDM1APARP1PARP10ADRA2ASRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925530-B 3, 4-dihydronaphthalene-1 (2H) -one compound, preparation method and application 滨州医学院 2024-03-12 CN claimed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-115925530-B 3, 4-dihydronaphthalene-1 (2H) -one compound, preparation method and application 滨州医学院 2024-03-12 CN disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed
CN-115925530-A 3,4-dihydronaphthalene-1 (2H) -ketone compound, preparation method and application 滨州医学院 2023-04-07 CN disclosed