SCHEMBL30344243

SCHEMBL30344243

COC(=O)c1cc2oc(CNC(=O)OC(C)(C)C)cc2cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4A O75164 1/20 0.38
TSHR P16473 2/20 0.38
ATR Q13535 1/20 0.36
KCNA5 P22460 1/20 0.35
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
BRD4 O60885 1/20 0.35
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25155268 1.00 ALDH1A1 (0.38) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL30344871 0.89 ALDH1A1 (0.39) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL30344452 0.80 HDAC3 (0.34) ALDH1A1HPGDKDM4ETSHRCA12
SCHEMBL25155552 0.80 HDAC3 (0.34) ALDH1A1HPGDKDM4ETSHRCA12
SCHEMBL29784510 0.79 ALDH1A1 (0.40) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL27185785 0.79 ALDH1A1 (0.40) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL16347843 0.78 STING1 (0.38) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL29784449 0.77 ESR2 (0.40) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL29784263 0.77 STING1 (0.42) ALDH1A1MAPTHPGDKDM4EGLA
SCHEMBL27185664 0.77 STING1 (0.53) ALDH1A1MAPTHPGDKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed