Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30537895 | 0.88 | MEN1 (0.39) | TSHRALDH1A1HSD17B10CA1KDM4E | |
| SCHEMBL30890423 | 0.83 | AKT1 (0.39) | LMNACA1POLBKMT2AMEN1 | |
| SCHEMBL30344873 | 0.81 | HDAC3 (0.42) | LMNAPOLBATMAKT1 | |
| SCHEMBL29425122 | 0.81 | NPC1 (0.46) | CA1KMT2AMEN1NPC1HTT | |
| SCHEMBL22615404 | 0.81 | NPC1 (0.46) | CA1KMT2AMEN1NPC1HTT | |
| SCHEMBL25156271 | 0.81 | HDAC3 (0.42) | LMNAPOLBATMAKT1 | |
| SCHEMBL361872 | 0.80 | MEN1 (0.38) | PDK2KMT2AMEN1NPC1HTT | |
| SCHEMBL30344367 | 0.80 | HDAC4 (0.46) | PDK2LMNATSHRALDH1A1CA1 | |
| SCHEMBL25156176 | 0.80 | HDAC4 (0.46) | PDK2LMNATSHRALDH1A1CA1 | |
| SCHEMBL31359913 | 0.78 | LPAR1 (0.39) | TSHRAKT1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216312-B | Compound with mutant IDH inhibitory activity, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2023-08-01 | — | — | CN | disclosed |