SCHEMBL30344380

SCHEMBL30344380

Cc1cc(F)c(OCC2CCN2C(=O)OC(C)(C)C)cc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SCN9A Q15858 2/20 0.42
▸ ALOX5AP P20292 3/20 0.38
▸ FEN1 P39748 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ DPP4 P27487 1/20 0.35
▸ F2RL3 Q96RI0 4/20 0.35
▸ LMNA P02545 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ TTR P02766 1/20 0.34
▸ GPR119 Q8TDV5 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31360409 1.00 SCN9A (0.42) SCN9AALOX5APFEN1SMN1; SMN2DPP4
SCHEMBL25156670 1.00 SCN9A (0.42) SCN9AALOX5APFEN1SMN1; SMN2DPP4
SCHEMBL30344047 0.90 SCN9A (0.45) SCN9AALOX5APFEN1DPP4F2RL3
SCHEMBL25156465 0.90 SCN9A (0.45) SCN9AALOX5APFEN1DPP4F2RL3
SCHEMBL31360255 0.84 LMNA (0.37) ALOX5APSMN1; SMN2F2RL3LMNANPSR1
SCHEMBL30344383 0.84 LMNA (0.37) ALOX5APSMN1; SMN2F2RL3LMNANPSR1
SCHEMBL25155387 0.81 ALOX5AP (0.43) ALOX5APFEN1LMNANPSR1GPR119
SCHEMBL31360281 0.81 ALOX5AP (0.43) ALOX5APFEN1LMNANPSR1GPR119
SCHEMBL25156353 0.81 ALOX5AP (0.43) ALOX5APFEN1LMNANPSR1GPR119
SCHEMBL30344023 0.81 ALOX5AP (0.43) ALOX5APFEN1LMNANPSR1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 — — US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD SCN9A 1682/4885ALOX5AP 456/4885FEN1 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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