Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344047 | 1.00 | SCN9A (0.45) | SCN9AALOX5APFEN1EEDRBBP4 | |
| SCHEMBL31360409 | 0.90 | SCN9A (0.42) | SCN9AALOX5APFEN1F2RL3LMNA | |
| SCHEMBL30344380 | 0.90 | SCN9A (0.42) | SCN9AALOX5APFEN1F2RL3LMNA | |
| SCHEMBL25156670 | 0.90 | SCN9A (0.42) | SCN9AALOX5APFEN1F2RL3LMNA | |
| SCHEMBL25155554 | 0.89 | PDE4A (0.38) | SCN9AEEDRBBP4SUZ12EZH2 | |
| SCHEMBL30344487 | 0.89 | PDE4A (0.38) | SCN9AEEDRBBP4SUZ12EZH2 | |
| SCHEMBL30344830 | 0.85 | PDGFRB (0.41) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL25155275 | 0.82 | LMNA (0.41) | ALOX5APEEDRBBP4SUZ12EZH2 | |
| SCHEMBL31360329 | 0.82 | LMNA (0.41) | ALOX5APEEDRBBP4SUZ12EZH2 | |
| SCHEMBL31360013 | 0.82 | LMNA (0.41) | ALOX5APEEDRBBP4SUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |