Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735052 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL10918583 | 0.89 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| Isobutane SCHEMBL27924537 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL28454940 | 0.84 | TDP1 (0.43) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL6421600 | 0.83 | TDP1 (0.40) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL19011804 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| Cyclohexane SCHEMBL27906530 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL19050231 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TDP1MEN1 | |
| SCHEMBL10914196 | 0.82 | SMN1; SMN2 (0.37) | ALDH1A1KMT2ATSHRMGAMGAA | |
| SCHEMBL10919488 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TSHRMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950770-B | Synthesis method of lacosamide | 珠海润都制药股份有限公司 | 2023-04-07 | — | — | CN | disclosed |