SCHEMBL6421600

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1748128	0.90	TDP1 (0.47)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL14925283	0.89	L3MBTL1 (0.40)	TDP1MEN1KMT2AALDH1A1LMNA
	Hydrochloric Acid SCHEMBL5274166	0.88	TDP1 (0.46)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL11735052	0.83	ALDH1A1 (0.42)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL30344784	0.83	ALDH1A1 (0.42)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL3010250	0.81	ALDH1A1 (0.44)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL482827	0.79	TDP1 (0.46)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL441261	0.79	ALDH1A1 (0.37)	TDP1ALDH1A1
	SCHEMBL839632	0.78	L3MBTL1 (0.45)	TDP1MEN1KMT2AALDH1A1LMNA
	SCHEMBL8912177	0.78	MEN1 (0.43)	TDP1MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.