Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162916 | 0.80 | KMO (0.46) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL1854888 | 0.78 | KMO (0.44) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL2029059 | 0.78 | KMO (0.44) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL3410551 | 0.76 | KMO (0.43) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL5215616 | 0.76 | KMO (0.43) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL536315 | 0.75 | KMO (0.45) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL28880099 | 0.74 | NCEH1 (0.43) | POLBTSHRNCEH1L3MBTL1NPSR1 | |
| SCHEMBL27801575 | 0.74 | KMO (0.41) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL19543121 | 0.74 | KMO (0.41) | POLBHSD17B10TSHRKMOL3MBTL1 | |
| SCHEMBL28251967 | 0.74 | KMO (0.41) | POLBHSD17B10TSHRKMOL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |