Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27642117 | 0.88 | KMO (0.47) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL19543170 | 0.85 | KMO (0.44) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL2029059 | 0.83 | KMO (0.44) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL1162916 | 0.83 | KMO (0.46) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL19543177 | 0.83 | KMO (0.43) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL19543175 | 0.81 | KMO (0.41) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL1854888 | 0.80 | KMO (0.44) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL19543176 | 0.80 | KMO (0.40) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL19543121 | 0.79 | KMO (0.41) | KMOPOLBHSD17B10TSHRASAH1 | |
| SCHEMBL27664784 | 0.79 | KMO (0.41) | KMOPOLBHSD17B10TSHRASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| WO-2014047662-A2 | INDAZOLE DERIVATIVES AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-03-27 | — | — | WO | disclosed |
| EP-2414375-A1 | NOVEL AMIDE DERIVATIVES OF STEROIDALÝ3,2-C¨PYRAZOLE COMPOUNDS WITH GLUCOCORTICOID ACTIVITY | AstraZeneca AB (SE) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114471-A1 | NOVEL AMIDE DERIVATIVES OF STEROIDAL[3,2-C]PYRAZOLE COMPOUNDS WITH GLUCOCORTICOID ACTIVITY | ASTRAZENECA AB (SE) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | KMO 4283/4885POLB 1298/4885HSD17B10 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.