SCHEMBL30344993

SCHEMBL30344993

Cc1cc([N+](=O)[O-])c(OCC2CCN2)cc1C(=O)NC1(c2cccc3ccccc23)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.34
▸ POLB P06746 2/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CTDSP1 Q9GZU7 1/20 0.34
▸ MYC P01106 1/20 0.33
▸ MAX P61244 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.32
▸ MAPK1 P28482 2/20 0.32
▸ LMNA P02545 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ RECQL P46063 1/20 0.32
▸ CHEK1 O14757 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ HTT P42858 1/20 0.32
▸ SIRT6 Q8N6T7 1/20 0.31
▸ IRAK4 Q9NWZ3 1/20 0.31
▸ HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30344494 0.87 SIRT6 (0.37) MAPTPOLBMEN1KMT2ACTDSP1
SCHEMBL31360459 0.82 CHRNB4 (0.40) —
SCHEMBL31360069 0.82 CHRNB4 (0.40) —
SCHEMBL25155299 0.82 CHRNB4 (0.40) —
SCHEMBL25155135 0.82 CHRNB4 (0.40) —
SCHEMBL25156257 0.82 CHRNB4 (0.40) —
SCHEMBL30344408 0.82 CHRNB4 (0.40) —
SCHEMBL31360031 0.82 ALDH1A1 (0.34) MAPTPOLBMEN1KMT2AALDH1A1
SCHEMBL30344514 0.82 ALDH1A1 (0.34) MAPTPOLBMEN1KMT2AALDH1A1
SCHEMBL31359901 0.82 MAPT (0.34) MAPTPOLBMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 — — US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD MAPT 1146/4885POLB 879/4885MEN1 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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